Prediction

    P3 - Toxin-like (mean score > 0.2 or mean score > 2*SD)
    P2 - Probably toxin-like (mean score > 0.2 or 2*SD > mean score > SD)
    P1 - Possibly toxin-like (mean score > -0.2 and mean score < SD)
    N - Probably not toxin-like (mean score < -0.2)

Scheme of the meta-classifier underlying ClanTox

Results for the classifier performance

Biological group Positive Total P-value
Toxin 299 541 6,72E-303
Neurotoxin 172 242 2,90E-197
Snake toxin 119 137 1,02E-154
Signal 379 2824 4,00E-134
Postsynaptic neurotoxin 76 99 3,36E-89
Phospholipase A2 83 171 1,20E-72
Knottin 62 81 3,83E-72
Serine protease inhibitor 105 324 1,13E-70
Acetylcholine receptor inhibitor 60 78 5,64E-70
Defensin 77 149 5,76E-70
Protease inhibitor 112 405 3,00E-67
Beta defensin 50 57 8,68E-64
Plant defense 69 132 6,88E-63
Antimicrobial 142 759 3,23E-62
Metal-thiolate cluster 64 123 5,52E-58
Antibiotic 125 656 3,44E-55
Snake cytotoxin 38 39 8,40E-53
Lipid degradation 71 188 3,08E-52
Gamma thionin 39 46 5,44E-48
Metallothionein superfamily 41 53 2,61E-47
S locus-related glycoprotein 1 binding pollen coat 34 35 7,40E-47
Whey acidic protein, core region 44 71 6,40E-44
Cardiotoxin 29 29 3,75E-40
Cyclotide 27 29 3,06E-35
Cadmium 28 34 3,78E-33
Gamma purothionin 26 29 9,32E-33
Vertebrate metallothionein 29 40 1,98E-31
Proteinase inhibitor I2, Kunitz metazoa 33 61 1,13E-29
Disintegrin 23 25 2,14E-29
Cell adhesion 32 62 7,80E-28
Calcium 70 409 1,28E-26
Cyclotide, bracelet 19 19 2,83E-25
Proteinase inhibitor I12, Bowman-Birk 23 33 7,16E-24
Fungicide 45 194 4,56E-22
Mammalian defensin 23 40 5,80E-21

More details are available in the (downloadable) articles: